Selection at behavioural, developmental and metabolic genes is associated with the northward expansion of a successful tropical colonizer.

Selection at behavioural, developmental and metabolic genes is associated with the northward expansion of a successful tropical colonizer.

What makes a species capable of colonize novel environments? This query is vital to grasp the dynamics of adaptive radiations and ecological area of interest shifts, however the mechanisms that underlie growth into novel habitats stay poorly understood at a genomic scale. Lizards from the genus Anolis are usually tropical, and the inexperienced anole (Anolis carolinensis) constitutes an exception because it expanded into temperate North America from subtropical Florida. Thus, we used the inexperienced anole as a mannequin to research signatures of choice related to colonization of a brand new atmosphere, particularly temperate North America. To this finish, we analysed 29 whole-genome sequences, masking all the native vary of the species.

We used a mix of latest strategies to quantify each constructive and balancing choice in northern populations, together with FST outlier strategies, machine studying and ancestral recombination graphs. We naively scanned for genes of curiosity and assessed the overlap between a number of checks. Strikingly, we recognized many genes concerned in behaviour, suggesting that the latest profitable colonization of northern environments might have been linked to behavioural shifts in addition to physiological adaptation. Utilizing a candidate genes technique, we decided that genes concerned in response to chilly or behaviour displayed extra often indicators of choice, whereas controlling for native recombination charge, gene clustering and gene size.

The Epigenetic Signature of Colonizing New Environments in Anolis Lizards.

Founder populations typically present fast divergence from supply populations after colonizing new environments. Epigenetic modifications can mediate phenotypic responses to environmental change and could also be an vital mechanism selling fast differentiation in founder populations. Whereas many long-term research have explored the extent to which divergence between supply and founder populations is genetically heritable versus plastic, the function of epigenetic processes throughout colonization stays unclear. To research epigenetic modifications in founding populations, we experimentally colonized eight small Caribbean islands with brown anole lizards (Anolis sagrei) from a standard supply inhabitants.
We then quantitatively measured genome-wide DNA methylation in liver tissue utilizing lowered illustration bisulfite sequencing of people transplanted onto islands with high- versus low-habitat high quality. We discovered that lizard intercourse and habitat high quality defined a major proportion of epigenetic variation. Differentially methylated cytosines mapped to genes that encode proteins with features more likely to be related to habitat change (e.g., sign transduction, immune response, circadian rhythm). This research gives experimental proof of a relationship between epigenetic responses and the earliest phases of colonization of novel environments in nature and means that habitat high quality influences the character of those epigenetic modifications.
Selection at behavioural, developmental and metabolic genes is associated with the northward expansion of a successful tropical colonizer.

Genetic Content material of the Neo-Intercourse Chromosomes in Ctenonotus and Norops (Squamata, Dactyloidae) and Degeneration of the Y Chromosome as Revealed by Excessive-Throughput Sequencing of Particular person Chromosomes.

Pleurodont lizards are characterised by an historical system of intercourse chromosomes. Together with stability of the central part of the system (homologous to the X chromosome of Anolis carolinensis [Dactyloidae], ACAX), in some genera the ancestral intercourse chromosomes are fused with microautosomes, forming neo-sex chromosomes. The genus Ctenonotus (Dactyloidae) is characterised by a number of X1X1X2X2/X1X2Y intercourse chromosomes.

Based on cytogenetic information, the massive neo-Y chromosome is fashioned by fusion of the ancestral Y chromosome with 2 microautosomes (homologous to ACA10 or ACA11 and ACA12), the X1 chromosome is fashioned by fusion of the ancestral X chromosome with the autosome homologous to ACA10 or ACA11, and the X2 chromosome is homologous to autosome ACA12. As well as, we discovered signatures of balancing choice at immune genes in all investigated genetic teams, but in addition at genes concerned in neuronal and anatomical improvement. Physique weights and meals consumption have been monitored and fecal samples have been collected for high-throughput 16S rRNA gene amplicon sequencing and analytical chemistry at days zero and 15.

To find out extra exactly the content material and evolution of the Ctenonotus intercourse chromosomes, we sequenced flow-sorted chromosomes (each intercourse chromosomes and microautosomes as management) of two species with an identical system: C. pogus and C. sabanus. Our outcomes point out that the translocated a part of the X1 is homologous to ACA11, X2 is homologous to ACA12, and the Y incorporates segments homologous to each ACA11 and ACA12. Molecular divergence estimates counsel that the ancestral X-derived half has fully degenerated within the Y of Ctenonotus, much like the degeneration of the Norops sagrei Y chromosome (Dactyloidae). The newly added areas present lack of DNA content material, however with out degeneration of the conserved areas. We hypothesize that the translocation of autosomal blocks onto intercourse chromosomes facilitated fast degeneration of the pseudoautosomal area on the ancestral Y.

Recombinant Estrogen Receptor Beta (ERb)

RPU41320-100ug 100ug
EUR 517

Recombinant Estrogen Receptor Beta (ERb)

RPU41320-1mg 1mg
EUR 2293.2

Recombinant Estrogen Receptor Beta (ERb)

RPU41320-50ug 50ug
EUR 415.8

Recombinant Estrogen Receptor Beta (ERb)

RPA437Hu01 10ug
EUR 120

Recombinant Estrogen Receptor Beta (ERb)

RPA437Mu01 10ug
EUR 168

Recombinant Estrogen Receptor Alpha (ERa)

4-RPB050Hu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Estrogen Receptor Alpha expressed in: E.coli

Recombinant Estrogen Receptor Alpha (ERa)

4-RPB050Hu02
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Estrogen Receptor Alpha expressed in: E.coli

Recombinant Estrogen Receptor Alpha (ERa)

4-RPB050Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Estrogen Receptor Alpha expressed in: E.coli

Recombinant Estrogen Receptor Alpha (ERa)

4-RPB050Ra01
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Estrogen Receptor Alpha expressed in: E.coli

Recombinant Estrogen Receptor Alpha (ERa)

RPU56877-100ug 100ug
EUR 470.4

Recombinant Estrogen Receptor Alpha (ERa)

RPU56877-1mg 1mg
EUR 2184

Recombinant Estrogen Receptor Alpha (ERa)

RPU56877-50ug 50ug
EUR 385

Recombinant Estrogen Receptor Alpha (ERa)

RPU55645-100ug 100ug
EUR 712.8

Recombinant Estrogen Receptor Alpha (ERa)

RPU55645-1mg 1mg
EUR 2808

Recombinant Estrogen Receptor Alpha (ERa)

RPU55645-50ug 50ug
EUR 432

Recombinant Estrogen Receptor Alpha (ERa)

RPU41318-100ug 100ug
EUR 591.8

Recombinant Estrogen Receptor Alpha (ERa)

RPU41318-1mg 1mg
EUR 2620.8

Recombinant Estrogen Receptor Alpha (ERa)

RPU41318-50ug 50ug
EUR 475.2

Recombinant Estrogen Receptor Alpha (ERa)

RPU53516-100ug 100ug
EUR 554.4

Recombinant Estrogen Receptor Alpha (ERa)

RPU53516-1mg 1mg
EUR 2457

Recombinant Estrogen Receptor Alpha (ERa)

RPU53516-50ug 50ug
EUR 445.5

Recombinant Estrogen Receptor Alpha (ERa)

RPU53018-100ug 100ug
EUR 542.3

Recombinant Estrogen Receptor Alpha (ERa)

RPU53018-1mg 1mg
EUR 2402.4

Recombinant Estrogen Receptor Alpha (ERa)

RPU53018-50ug 50ug
EUR 435.6

Recombinant Estrogen Receptor Alpha (ERa)

RPB050Hu01 10ug
EUR 180

Recombinant Estrogen Receptor Alpha (ERa)

RPB050Hu02 10ug
EUR 180

Recombinant Estrogen Receptor Alpha (ERa)

RPB050Mu01 10ug
EUR 176

Recombinant Estrogen Receptor Alpha (ERa)

RPB050Ra01 10ug
EUR 192

Recombinant Human Estrogen Receptor Alpha

7-05092 2µg Ask for price

Recombinant Human Estrogen Receptor Alpha

7-05093 5µg Ask for price

Recombinant Human Estrogen Receptor Alpha

7-05094 10µg Ask for price

Estrogen Receptor beta Recombinant Protein

92-106 0.05 mg
EUR 651.3
Description: Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Estrogen receptor alpha Recombinant Protein

91-978 0.05 mg
EUR 821.4
Description: Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Recombinant Human Estrogen Receptor Protein

RP00815 10 μg
EUR 265.2

Recombinant (E.Coli) Human Estrogen Receptor Alpha

RP-940 2 ug
EUR 416.4

Recombinant Human Estrogen receptor (ESR1) ,partial

RPC24652-100ug 100ug
EUR 465.3

Recombinant Human Estrogen receptor (ESR1) ,partial

RPC24652-20ug 20ug
EUR 288.8

Recombinant Human Estrogen receptor(ESR1),partial

AP72550 each Ask for price

Recombinant Human Estrogen receptor (ESR1), partial

CSB-YP007830HU 5641 mg Ask for price

Recombinant Human Estrogen receptor (ESR1), partial

CSB-YP007830HU1 9744 mg Ask for price

Recombinant Human Estrogen Receptor Protein, His Tag

E40KMP1674 20ug
EUR 495

Recombinant Mouse Estrogen receptor (Esr1), Biotinylated

CSB-EP007830MO-B 9387 mg Ask for price

Estrogen Receptor beta recombinant monoclonal antibody

A5691 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Estrogen Receptor beta for WB ,ELISA

Recombinant Human Estrogen receptor beta (ESR2) ,partial

RPC21281-100ug 100ug
EUR 460.9

Recombinant Human Estrogen receptor beta (ESR2) ,partial

RPC21281-1mg 1mg
EUR 2237.8

Recombinant Human Estrogen receptor beta (ESR2) ,partial

RPC21281-20ug 20ug
EUR 258.7

Recombinant Human Estrogen receptor beta(ESR2),partial

AP76517 1mg
EUR 1978

Recombinant Human Estrogen receptor beta(ESR1),partial

AP72551 1mg
EUR 2303

Recombinant Human Estrogen receptor beta(ESR2),partial

AP76608 1mg
EUR 1978

Recombinant Human Estrogen receptor beta (ESR2), partial

CSB-EP007831HU1 1123 mg Ask for price

Recombinant Human Estrogen receptor beta (ESR2), partial

CSB-EP007831HU1a2 1124 mg Ask for price

Recombinant Human Estrogen receptor beta (ESR2), partial

CSB-YP007831HU 5642 mg Ask for price

Recombinant Estrogen Related Receptor Beta (ERRb)

4-RPD961Mu01
  • EUR 603.84
  • EUR 285.60
  • EUR 1934.40
  • EUR 724.80
  • EUR 1329.60
  • EUR 480.00
  • EUR 4656.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Estrogen Related Receptor Beta expressed in: E.coli

Recombinant Estrogen Related Receptor Beta (ERRb)

RPU53637-100ug 100ug
EUR 554.4

Recombinant Estrogen Related Receptor Beta (ERRb)

RPU53637-1mg 1mg
EUR 2457

Recombinant Estrogen Related Receptor Beta (ERRb)

RPU53637-50ug 50ug
EUR 445.5

Recombinant Estrogen Related Receptor Beta (ERRb)

RPD961Mu01 10ug
EUR 180

Recombinant Estrogen Related Receptor Alpha (ERRa)

RPD960Hu01 10ug
EUR 140

OPCA01236-1MG - Recombinant human Estrogen receptor beta

OPCA01236-1MG 1mg
EUR 1606

OPCA01236-20UG - Recombinant human Estrogen receptor beta

OPCA01236-20UG 20ug
EUR 258

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU58573-100ug 100ug
EUR 580.5

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU58573-1mg 1mg
EUR 2695.7

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU58573-50ug 50ug
EUR 451.4

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU57458-100ug 100ug
EUR 470.4

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU57458-1mg 1mg
EUR 2184

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPU57458-50ug 50ug
EUR 385

Recombinant Human Estrogen Receptor/ESR1 Protein, His Tag

E40KMH1054 20ug
EUR 495

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPG045Hu01 10ug
EUR 173

Recombinant G Protein Coupled Estrogen Receptor 1 (GPER)

RPG045Mu01 10ug
EUR 140

OPCA01236-100UG - Recombinant human Estrogen receptor beta

OPCA01236-100UG 100ug
EUR 380

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

CF53-10ug 10ug
EUR 187.2
Description: Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl,pH8.0.

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

CF53-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl,pH8.0.

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

CF53-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl,pH8.0.

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

CF53-50ug 50ug
EUR 442.8
Description: Lyophilized from a 0.2 μm filtered solution of 50mM TrisHCl,pH8.0.

Recombinant Human Estrogen Receptor α/ERα/NR3A1 (N-6His)

CE11-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Estrogen Receptor α/ERα/NR3A1 (N-6His)

CE11-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Estrogen Receptor α/ERα/NR3A1 (N-6His)

CE11-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Estrogen Receptor α/ERα/NR3A1 (N-6His)

CE11-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Recombinant Human Estrogen Receptor β/ERβ/NR3A2 (N-6His)

AP75800 1mg
EUR 3209

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-1mg

QP6000-ye-1mg 1mg
EUR 2262

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-10ug

QP6000-ye-10ug 10ug
EUR 283.2

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-50ug

QP6000-ye-50ug 50ug
EUR 358.8

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-100ug

QP6000-ye-100ug 100ug
EUR 576

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-200ug

QP6000-ye-200ug 200ug
EUR 892.8

Recombinant Human Estrogen Receptor 2 Protein, His, Yeast-500ug

QP6000-ye-500ug 500ug
EUR 1447.2

Recombinant Human Estrogen Receptor Binding Site Associated Antigen 9

7-05023 10µg Ask for price

Recombinant Human Estrogen Receptor Binding Site Associated Antigen 9

7-05024 50µg Ask for price

Recombinant Human Estrogen Receptor Binding Site Associated Antigen 9

7-05025 1mg Ask for price

Human Estrogen Receptor Binding Site Associated Antigen 9 (Recombinant)

22060271-1 10 µg
EUR 200.37

Human Estrogen receptor alpha Recombinant Protein N-6 His Tag Lyophilized

IHUESRARN6HISLY50UG each
EUR 988
Description: Human Estrogen receptor alpha Recombinant Protein N-6 His Tag Lyophilized

Human Estrogen Receptor beta Recombinant Protein N-6 His Tag Lyophilized

IHUESRRBRN6HISLY50UG each
EUR 762
Description: Human Estrogen Receptor beta Recombinant Protein N-6 His Tag Lyophilized

Bacteria-Derived Estrogen Receptor alpha Recombinant Protein N-6His Tag Lyophilized

IBCTESR1RN6HISLY10UG each
EUR 202
Description: Bacteria-Derived Estrogen Receptor alpha Recombinant Protein N-6His Tag Lyophilized

Estrogen Receptor-

ABF8113 100 ug
EUR 525.6

Estrogen Receptor-

ABF8235 100 ug
EUR 525.6

Estrogen Receptor

MC-245 SP1 Ask for price

Estrogen receptor

AP78779 1mg
EUR 2640

Estrogen receptor

AP89387 1mg
EUR 2640

Estrogen receptor

AP82694 1mg
EUR 2640

Estrogen receptor

AP82997 1mg
EUR 2640

Estrogen receptor

AP83068 1mg
EUR 2640

Estrogen receptor

AP83219 1mg
EUR 2640

Estrogen Receptor beta

E8ET1701-69 100ul
EUR 275
Description: Available in various conjugation types.

Estrogen receptor beta

AP79339 1mg
EUR 2640

Estrogen receptor beta

AP82716 1mg
EUR 2640

Estrogen receptor beta

AP82847 1mg
EUR 2640

Estrogen receptor beta

AP82861 1mg
EUR 2640

Estrogen receptor beta

AP82982 1mg
EUR 2640

Estrogen receptor beta

AP83069 1mg
EUR 2640

Estrogen Receptor alpha

E8RE6030 100ul
EUR 275
Description: Available in various conjugation types.

Estrogen Receptor alpha

E8ER1803-83 100ul
EUR 275
Description: Available in various conjugation types.

estrogen receptor protein

E20-80123 20ug
EUR 489.6

Estrogen Receptor antibody

10R-2015 100 ul
EUR 483.6
Description: Mouse monoclonal Estrogen Receptor antibody

Estrogen Receptor antibody

10R-2109 100 ul
EUR 418.8
Description: Mouse monoclonal Estrogen Receptor antibody

Estrogen Receptor antibody

10R-2143 100 ul
EUR 418.8
Description: Mouse monoclonal Estrogen Receptor antibody

Estrogen Receptor antibody

10R-E117a 100 ug
EUR 548.4
Description: Mouse monoclonal Estrogen Receptor antibody

Estrogen Receptor antibody

10R-E118a 100 ug
EUR 620.4
Description: Mouse monoclonal Estrogen Receptor antibody

Estrogen Receptor antibody

20R-ER006 500 ul
EUR 1227.6
Description: Rabbit polyclonal Estrogen Receptor antibody

Estrogen Receptor antibody

20R-ER007 500 ul
EUR 613.2
Description: Rabbit polyclonal Estrogen Receptor antibody

Estrogen Receptor Antibody

F43055-0.4ML 0.4 ml
EUR 322.15
Description: This gene encodes an Estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. ERs are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Estrogen Receptor Antibody

F47523-0.4ML 0.4 ml
EUR 322.15
Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Estrogen receptor-IN-1

T60293-10mg 10mg Ask for price
Description: Estrogen receptor-IN-1

Estrogen receptor-IN-1

T60293-1g 1g Ask for price
Description: Estrogen receptor-IN-1

Estrogen receptor-IN-1

T60293-1mg 1mg Ask for price
Description: Estrogen receptor-IN-1

Estrogen receptor-IN-1

T60293-50mg 50mg Ask for price
Description: Estrogen receptor-IN-1

Estrogen receptor-IN-1

T60293-5mg 5mg Ask for price
Description: Estrogen receptor-IN-1

Anti-ER (Estrogen Receptor)

DB-053-0.1 100 μl
EUR 289.2
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-ER (Estrogen Receptor)

DB-053-0.2 200 μl
EUR 409.2
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-ER (Estrogen Receptor)

DB-053-0.5 500 μl
EUR 529.2
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-ER (Estrogen Receptor)

DB-053-1 1 ml
EUR 850.8
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Anti-ER (Estrogen Receptor)

DB-053-RTU-15 15 ml
EUR 487.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-ER (Estrogen Receptor)

DB-053-RTU-7 7 ml
EUR 314.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-ER (Estrogen Receptor)

DB-1015 100 tests
EUR 654

Anti-ER (Estrogen Receptor)

DB053RTU-15 15 ml
EUR 487.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-ER (Estrogen Receptor)

DB053RTU-7 7 ml
EUR 314.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Microbiome research targeted on ecologically related vertebrate fashions like reptiles have been restricted. Due to their comparatively small residence vary, quick maturation, and excessive fecundity, lizards are a superb reptilian terrestrial indicator species. For this research we used the inexperienced anole, Anolis carolinensis, to evaluate the impression of navy related contaminants on fecal microbiome composition. Fourteen day sub-acute exposures have been carried out by way of oral gavage with 2,4,6-Trinitrotoluene (TNT) and inorganic lead at doses of 60 mg/kg and 20 mg/kg of physique weight, respectively.

Detection of genes positively selected in Cuban Anolis lizards that naturally inhabit hot and open areas and currently thrive in urban areas

Detection of genes positively selected in Cuban Anolis lizards that naturally inhabit hot and open areas and currently thrive in urban areas

Species of Anolis lizards of the West Indies that naturally inhabit sizzling and open areas additionally are likely to thrive in city areas. On this research, transcriptome was sequenced for 9 species of Cuban Anolis lizards which are intently associated to one another, however inhabit completely different thermal microhabitats. Utilizing PAML and HyPhy software program, we tried to establish genes and amino acid websites below constructive choice within the frequent ancestral department of A. porcatus and A. allisoni, and the department of A. sagrei, which inhabit sizzling and open areas, and thrive in city areas. We offer proof for the lack of a multi-exonic plasminogen receptor KT (PLGRKT) protein-encoding gene situated on the Z chromosome in hen.

Though there have been no genes the place constructive choice was generally detected on each of the examined branches, constructive choice was detected in genes concerned within the stress response (e.g., DNA harm and oxidative stress) and cardiac operate, which could possibly be associated to adaptive evolution of tolerance to warmth or ultraviolet radiation, on each branches. These findings counsel that adaptive evolution of the response to emphasize attributable to warmth or ultraviolet radiation might need occurred in ancestors of Anolis species inhabiting sizzling and open areas and could be associated to the present thriving in city areas of them.

The lack of conserved genes has the potential to change phenotypes drastically. Screening of vertebrate genomes for lineage-specific gene loss occasions has recognized quite a few pure knockouts related to particular phenotypes. Exons 1 and a pair of are solely lacking; remnants of exon three and a largely intact exon four are recognized in an meeting gap-free area in hen with conserved synteny throughout species and verified utilizing transcriptome and genome sequencing. PLGRKT gene disrupting adjustments are current in consultant species from all 5 galliform households. In distinction to this, the presence of an intact transcriptionally lively PLGRKT gene in species corresponding to mallard, swan goose, and Anolis lizard means that gene loss occurred within the galliform lineage someday between 68 and 80 Mya. The presence of galliform particular hen repeat 1 (CR1) insertion on the erstwhile exon 2 of PLGRKT gene suggests repeat insertion-mediated loss.

Transcriptome sequencing reveals signatures of constructive choice within the Spot-Tailed Earless Lizard

The continuous lack of threatened biodiversity is going on at an accelerated tempo. Excessive-throughput sequencing applied sciences at the moment are offering alternatives to deal with this subject by aiding within the technology of molecular information for a lot of understudied species of excessive conservation curiosity. Our total purpose of this research was to start constructing the genomic assets to proceed investigations and conservation of the Spot-Tailed Earless lizard. Right here we leverage the facility of high-throughput sequencing to generate the liver transcriptome for the Northern Spot-Tailed Earless Lizard (Holbrookia lacerata) and Southern Spot-Tailed Earless Lizard (Holbrookia subcaudalis), which have declined in abundance prior to now a long time, and their sister species, the Frequent Lesser Earless Lizard (Holbrookia maculata).

Our efforts produced top quality and strong transcriptome assemblies validated by 1) quantifying the variety of processed reads represented within the transcriptome meeting and a pair of) quantifying the variety of extremely conserved single-copy orthologs which are current in our transcript set utilizing the BUSCO pipeline. We discovered 1,361 1-to-1 orthologs among the many three Holbrookia species, Anolis carolinensis, and Sceloporus undulatus. We carried out dN/dS choice exams utilizing a branch-sites mannequin and recognized a dozen genes that skilled constructive choice within the Holbrookia lineage with capabilities in improvement, immunity, and metabolism. Our single-copy orthologous sequences moreover revealed important pairwise sequence divergence (~.73%) between the Northern H. lacerata and Southern H. subcaudalis that additional helps the current elevation of the Southern Spot-Tailed Earless Lizard to full species.

Detection of genes positively selected in Cuban Anolis lizards that naturally inhabit hot and open areas and currently thrive in urban areas

First report of intercourse chromosomes in night time lizards (Scincoidea: Xantusiidae).

Squamate reptiles (lizards, snakes, and amphisbaenians) are an impressive group for finding out intercourse chromosome evolution-they are previous, speciose, geographically widespread, and exhibit myriad intercourse figuring out modes. But, the overwhelming majority of squamate species lack heteromorphic intercourse chromosomes. Cataloguing the intercourse chromosome methods of species missing simply identifiable, heteromorphic intercourse chromosomes, due to this fact, is crucial earlier than we’re to completely perceive the evolution of vertebrate intercourse chromosomes.
Right here, we use restriction-site related DNA sequencing (RADseq) to categorise the intercourse chromosome system of the granite night time lizard, Xantusia henshawi. RADseq is an efficient different to conventional cytogenetic strategies for figuring out a species’ intercourse chromosome system (i.e. XX/XY or ZZ/ZW), significantly in taxa with non-differentiated intercourse chromosomes. Though many xantusiid lineages have been karyotyped, none possess heteromorphic intercourse chromosomes. We recognized a ZZ/ZW intercourse chromosome system in X. henshawi-the first such information for this household. Moreover, we report that the X. henshawi intercourse chromosome comprises fragments of genes discovered on Gallus gallus chromosomes 7, 12, and 18 (that are homologous to Anolis carolinensis chromosome 2), the primary vertebrate intercourse chromosomes to make the most of this linkage group.

Recombinant Human Fatty Acid Binding Protein-2

7-05120 25µg Ask for price

Recombinant Human Fatty Acid Binding Protein-2

7-05121 1mg Ask for price

Recombinant Human Fatty Acid Binding Protein-3

7-05122 5µg Ask for price

Recombinant Human Fatty Acid Binding Protein-3

7-05123 20µg Ask for price

Recombinant Human Fatty Acid Binding Protein-3

7-05124 1mg Ask for price

Recombinant Human Fatty Acid Binding Protein-4

7-05128 2µg Ask for price

Recombinant Human Fatty Acid Binding Protein-4

7-05129 10µg Ask for price

Recombinant Human Fatty Acid Binding Protein-4

7-05130 1mg Ask for price

Recombinant Human Fatty Acid Binding Protein-5

7-05134 2µg Ask for price

Recombinant Human Fatty Acid Binding Protein-5

7-05135 10µg Ask for price

Recombinant Human Fatty Acid Binding Protein-5

7-05136 1mg Ask for price

Recombinant Human Fatty Acid Binding Protein-6

7-05140 5µg Ask for price

Recombinant Human Fatty Acid Binding Protein-6

7-05141 20µg Ask for price

Recombinant Human Fatty Acid Binding Protein-6

7-05142 1mg Ask for price

Recombinant Human Fatty Acid Binding Protein-7

7-05146 5µg Ask for price

Recombinant Human Fatty Acid Binding Protein-7

7-05147 25µg Ask for price

Recombinant Human Fatty Acid Binding Protein-7

7-05148 1mg Ask for price

Human Fatty Acid Binding Protein-3 (Recombinant)

22060323-1 5 µg
EUR 137.27

Fatty Acid Binding Protein-1 Human (Recombinant)

22060987-1 5 µg
EUR 137.27

Fatty Acid Binding Protein-6 Human (Recombinant)

22060994-1 5 µg
EUR 137.27

Fatty Acid Binding Protein-7 Human (Recombinant)

22060996-1 5 µg
EUR 137.27

Recombinant Human Fatty acid binding protein-3

AP60475 100ug
EUR 939

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41354-100ug 100ug
EUR 393.8

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41354-1mg 1mg
EUR 1747.2

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41354-50ug 50ug
EUR 316.8

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41355-100ug 100ug
EUR 517

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41355-1mg 1mg
EUR 2293.2

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41355-50ug 50ug
EUR 415.8

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41356-100ug 100ug
EUR 517

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41356-1mg 1mg
EUR 2293.2

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41356-50ug 50ug
EUR 415.8

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41357-100ug 100ug
EUR 492.8

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41357-1mg 1mg
EUR 2184

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU41357-50ug 50ug
EUR 396

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41364-100ug 100ug
EUR 369.6

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41364-1mg 1mg
EUR 1638

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41364-50ug 50ug
EUR 297

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41365-100ug 100ug
EUR 504.9

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41365-1mg 1mg
EUR 2238.6

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41365-50ug 50ug
EUR 405.9

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41366-100ug 100ug
EUR 431.2

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41366-1mg 1mg
EUR 1911

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41366-50ug 50ug
EUR 346.5

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41367-100ug 100ug
EUR 554.4

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41367-1mg 1mg
EUR 2457

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU41367-50ug 50ug
EUR 445.5

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41368-100ug 100ug
EUR 393.8

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41368-1mg 1mg
EUR 1747.2

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41368-50ug 50ug
EUR 316.8

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41369-100ug 100ug
EUR 492.8

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41369-1mg 1mg
EUR 2184

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41369-50ug 50ug
EUR 396

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41370-100ug 100ug
EUR 517

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41370-1mg 1mg
EUR 2293.2

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU41370-50ug 50ug
EUR 415.8

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU54530-100ug 100ug
EUR 603.9

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU54530-1mg 1mg
EUR 2675.4

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU54530-50ug 50ug
EUR 485.1

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54613-100ug 100ug
EUR 616

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54613-1mg 1mg
EUR 2730

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54613-50ug 50ug
EUR 495

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54614-100ug 100ug
EUR 616

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54614-1mg 1mg
EUR 2730

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPU54614-50ug 50ug
EUR 495

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU50986-100ug 100ug
EUR 443.3

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU50986-1mg 1mg
EUR 1965.6

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU50986-50ug 50ug
EUR 356.4

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU57855-100ug 100ug
EUR 508.2

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU57855-1mg 1mg
EUR 2358.7

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPU57855-50ug 50ug
EUR 415.8

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55709-100ug 100ug
EUR 633.6

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55709-1mg 1mg
EUR 2496

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55709-50ug 50ug
EUR 384

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55710-100ug 100ug
EUR 633.6

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55710-1mg 1mg
EUR 2496

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU55710-50ug 50ug
EUR 384

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU56400-100ug 100ug
EUR 293.2

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU56400-1mg 1mg
EUR 1360.4

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPU56400-50ug 50ug
EUR 209.3

Recombinant Fatty Acid Binding Protein 4 (FABP4)

4-RPB693Bo01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Bovine Fatty Acid Binding Protein 4 expressed in: E.coli

Recombinant Fatty Acid Binding Protein 4 (FABP4)

4-RPB693Ov01
  • EUR 550.08
  • EUR 271.20
  • EUR 1732.80
  • EUR 657.60
  • EUR 1195.20
  • EUR 444.00
  • EUR 4152.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Sheep Fatty Acid Binding Protein 4 expressed in: E.coli

Fatty Acid Binding Protein 2 Human (Recombinant)

22060988-1 5 µg
EUR 137.27

Fatty Acid Binding Protein 4 Human (Recombinant)

22060990-1 2 µg
EUR 137.27

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Bo01 10ug
EUR 200

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Ga01 10ug
EUR 168

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Hu01 10ug
EUR 128

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Mu01 10ug
EUR 160

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Po01 10ug
EUR 200

Recombinant Fatty Acid Binding Protein 1 (FABP1)

RPB566Ra01 10ug
EUR 168

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Bo01 10ug
EUR 160

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Ga01 10ug
EUR 144

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Hu01 10ug
EUR 120

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Mu01 10ug
EUR 140

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Ov01 10ug
EUR 160

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Po01 10ug
EUR 180

Recombinant Fatty Acid Binding Protein 4 (FABP4)

RPB693Ra01 10ug
EUR 164

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPB985Hu01 10ug
EUR 128

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPB985Mu01 10ug
EUR 160

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPB985Po01 10ug
EUR 196

Recombinant Fatty Acid Binding Protein 5 (FABP5)

RPB985Ra01 10ug
EUR 168

Recombinant Human Fatty Acid Binding Protein-12

7-05152 2µg Ask for price

Recombinant Human Fatty Acid Binding Protein-12

7-05153 10µg Ask for price

Recombinant Human Fatty Acid Binding Protein-12

7-05154 1mg Ask for price

Epidermal Fatty Acid Binding Protein Human Recombinant

22060992-1 2 µg
EUR 137.27

Recombinant (E.Coli) Human Fatty Acid Binding Protein-3

RP-804 5 ug
EUR 196.8

Recombinant (E.Coli) Human Fatty Acid Binding Protein-4

RP-865 10 ug
EUR 343.2

Recombinant (E.Coli) Human Fatty Acid Binding Protein-5

RP-867 10 ug
EUR 343.2

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

4-RPA344Hu01
  • EUR 582.34
  • EUR 279.60
  • EUR 1853.76
  • EUR 697.92
  • EUR 1275.84
  • EUR 465.60
  • EUR 4454.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Fatty Acid Binding Protein 6, Ileal expressed in: E.coli

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

4-RPA344Mu01
  • EUR 593.09
  • EUR 282.00
  • EUR 1894.08
  • EUR 711.36
  • EUR 1302.72
  • EUR 472.80
  • EUR 4555.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Fatty Acid Binding Protein 6, Ileal expressed in: E.coli

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

4-RPA344Po01
  • EUR 625.34
  • EUR 290.40
  • EUR 2015.04
  • EUR 751.68
  • EUR 1383.36
  • EUR 494.40
  • EUR 4857.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pig Fatty Acid Binding Protein 6, Ileal expressed in: E.coli

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

4-RPA344Ra01
  • EUR 608.14
  • EUR 286.80
  • EUR 1950.53
  • EUR 730.18
  • EUR 1340.35
  • EUR 482.40
  • EUR 4696.32
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Fatty Acid Binding Protein 6, Ileal expressed in: E.coli

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU41371-100ug 100ug
EUR 558.8

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU41371-1mg 1mg
EUR 2479.1

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU41371-50ug 50ug
EUR 449.9

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41372-100ug 100ug
EUR 431.2

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41372-1mg 1mg
EUR 1911

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41372-50ug 50ug
EUR 346.5

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41373-100ug 100ug
EUR 431.2

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41373-1mg 1mg
EUR 1911

Recombinant Fatty Acid Binding Protein 7, Brain (FABP7)

RPU41373-50ug 50ug
EUR 346.5

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU54153-100ug 100ug
EUR 578.6

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU54153-1mg 1mg
EUR 2566.2

Recombinant Fatty Acid Binding Protein 6, Ileal (FABP6)

RPU54153-50ug 50ug
EUR 465.3
The transcription issue Pax6 is essential for the event of the central nervous system, eye, olfactory system and pancreas, and is implicated in human illness. Whereas a single Pax6 gene exists in human and hen, Pax6 happens as a gene household in different vertebrates, with two members in elephant shark, Xenopus tropicalis and Anolis lizard and three members in teleost fish corresponding to stickleback and medaka. Nevertheless, the complement of Pax6 genes in jawless vertebrates (cyclostomes), the sister group of jawed vertebrates (gnathostomes), is unknown. Utilizing a mix of BAC sequencing and genome evaluation, we found three Pax6 genes in lampreys.