Squamates include all lizards and snakes, and display some of the most diverse and extreme morphological adaptations among vertebrates. However, compared with birds and mammals, relatively few resources exist for comparative genomic analyses of squamates, hampering efforts to understand the molecular bases of phenotypic diversification in such a speciose clade.
In particular, the ∼400 species of anolelizard represent an extensive squamate radiation. Here, we sequence and assemble the draft genomes of three anole species-Anolis frenatus, Anolis auratus, and Anolis apletophallus-for comparison with the available reference genome of Anolis carolinensis. Comparative analyses reveal a rapid background rate of molecular evolution consistent with a model of punctuated equilibrium, and strong purifying selection on functional genomic elements in anoles.
We find evidence for accelerated evolution in genes involved in behavior, sensory perception, and reproduction, as well as in genes regulating limb bud development and hindlimb specification. Morphometric analyses of anole fore and hindlimbs corroborated these findings.
HSP70 ELISA Kit |
SKT-105-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2260 |
|
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Cell Lysates, Tissue, Serum, Urine samples from Human, Goat, Dog |
HSC70 ELISA Kit |
SKT-106-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2836 |
|
Description: Sandwich ELISA kit used for quantitate HSC70 concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Avian |
HSP90 alpha ELISA Kit |
SKT-107-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2702 |
|
Description: Sandwich ELISA kit used for quantitate HSP90 alpha concentration in Cell Lysates, Tissue, Serum, Whole Blood samples from Human, Goat, Avian |
HSP70 ELISA Kit (High-Sensitivity) |
SKT-108-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2702 |
|
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human, Monkey, Dog, Rat, Mouse |
HSP27 ELISA Kit |
SKT-109-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2277 |
|
Description: Sandwich ELISA kit used for quantitate HSP27 concentration in Serum, Plasma, Cell Lysates, Tissue samples from Human |
HSP60 ELISA Kit |
SKT-110-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2277 |
|
Description: Sandwich ELISA kit used for quantitate HSP60 concentration in Cell Lysates, Tissue, Serum samples from Human |
HSP65 ELISA Kit |
SKT-113-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2478 |
|
Description: Sandwich ELISA kit used for quantitate M bovis/M tuberculosum HSP65 concentration in human samples in Cell Lysates, Tissue, Serum samples from M bovis, M tuberculosum |
Alpha B Crystallin ELISA Kit |
SKT-123-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2836 |
|
Description: Sandwich ELISA kit used for quantitate alpha B crystallin concentration in Cell Lysates, Tissue, Serum samples from Human |
HSP70 ELISA Kit (PLANT) |
SKT-124-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2836 |
|
Description: Sandwich ELISA kit used for quantitate HSP70 concentration in Plant extract, Cell Lysates, Tissue, Serum, Plasma samples from Plant, Human |
Nitrotyrosine ELISA Kit |
SKT-126-480 |
Stressmarq |
5 plates of 96 wells |
EUR 1747 |
|
Description: Competitive ELISA kit used for quantitate Nitrotyrosine in Plasma, Serum, Cell Lysates, Urine samples from all species |
Rat GRP78 ELISA Kit |
SKT-137-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2474 |
|
Description: Sandwich ELISA kit used for quantitate GRP78 concentration in rat samples in Tissue samples from Rat |
Dibromo-tyrosine ELISA Kit |
SKT-140-480 |
Stressmarq |
5 plates of 96 wells |
EUR 2195 |
|
Description: Competitive ELISA kit used to quantify free and protein-bound 3,5-dibromotyrosine in Plasma, Urine samples from all species |
HO-1 ELISA Kit |
SKT-111-96 |
Stressmarq |
1 plate of 96 wells |
EUR 585 |
|
Description: Sandwich ELISA kit used for quantitate HO-1 concentration in Cell Lysates, Tissue, Serum, Cyst fluid samples from Human, Rat |
Mouse SKT shRNA Plasmid |
20-abx980555 |
Abbexa |
|
|
|
JW 480 |
B5556-10 |
ApexBio |
10 mg |
EUR 167 |
JW 480 |
B5556-25 |
ApexBio |
25 mg |
EUR 325 |
JW 480 |
B5556-5 |
ApexBio |
5 mg |
EUR 110 |
JW 480 |
B5556-50 |
ApexBio |
50 mg |
EUR 540 |
Sulforhodamine 101 sulfonyl chloride [Texas Red®] *CAS 82354-19-6* |
480 |
AAT Bioquest |
10 mg |
EUR 132 |
|
Mouse Sickle tail protein (SKT) ELISA Kit |
abx389166-96tests |
Abbexa |
96 tests |
EUR 911 |
|
Superior Prime Broth™ |
111 |
AthenaES |
500 g |
EUR 110 |
Human Sickle tail protein homolog, SKT ELISA KIT |
ELI-18163h |
Lifescience Market |
96 Tests |
EUR 824 |
Handheld Fluorometer 480/530nm |
FL480530 |
BioAssay Systems |
1 unit |
EUR 1572 |
Description: Compact handheld fluorometer (exc.480 and em.530nm) for quantitative determination of various analytes in life sciences R&D, food safety and environmental monitoring. Highly sensitive, rapid-reading, reliable and low cost. |
Skt ELISA Kit| Mouse Sickle tail protein ELISA Kit |
EF014796 |
Lifescience Market |
96 Tests |
EUR 689 |
Polyclonal ADD3 Antibody (aa431-480) |
APR14821G |
Leading Biology |
0.05ml |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ADD3 (aa431-480). This antibody is tested and proven to work in the following applications: |
CD45RA(111-1C5) Antibody |
BNCA1038-250 |
Biotium |
250uL |
EUR 383 |
Description: Primary antibody against CD45RA(111-1C5), APC conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC811038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF680R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC811038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF680R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCAP1038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCAP1038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCB1038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), Biotin conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCB1038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), Biotin conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC471038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF647 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC471038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF647 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC551038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF555 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC551038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF555 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC431038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF543 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC431038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF543 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC881038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF488A conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC881038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF488A conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC941038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF594 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC941038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF594 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCP1038-250 |
Biotium |
250uL |
EUR 383 |
Description: Primary antibody against CD45RA(111-1C5), PerCP conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC041038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF405S conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC041038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF405S conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC051038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF405M conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC051038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF405M conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCR1038-250 |
Biotium |
250uL |
EUR 383 |
Description: Primary antibody against CD45RA(111-1C5), RPE conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNUB1038-100 |
Biotium |
100uL |
EUR 209 |
Description: Primary antibody against CD45RA(111-1C5), Concentration: 0.2mg/mL |
CD45RA(111-1C5) Antibody |
BNUB1038-500 |
Biotium |
500uL |
EUR 458 |
Description: Primary antibody against CD45RA(111-1C5), Concentration: 0.2mg/mL |
CD45RA(111-1C5) Antibody |
BNC681038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF568 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC681038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF568 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC701038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF770 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC701038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF770 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC611038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF660R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC611038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF660R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC401038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF640R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC401038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF640R conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC801038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), CF680 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNC801038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), CF680 conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCH1038-100 |
Biotium |
100uL |
EUR 199 |
Description: Primary antibody against CD45RA(111-1C5), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNCH1038-500 |
Biotium |
500uL |
EUR 544 |
Description: Primary antibody against CD45RA(111-1C5), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
CD45RA(111-1C5) Antibody |
BNUM1038-50 |
Biotium |
50uL |
EUR 395 |
Description: Primary antibody against CD45RA(111-1C5), 1mg/mL |
Monoclonal CGA / hCG Alpha Antibody (clone ME.111), Clone: ME.111 |
APG02560G |
Leading Biology |
0.1mg |
EUR 484 |
Description: A Monoclonal antibody against Human CGA / hCG Alpha (clone ME.111). The antibodies are raised in Mouse and are from clone ME.111. This antibody is applicable in WB and IHC-P, E |
Zinc Finger Protein 480 (ZNF480) Antibody |
20-abx116741 |
Abbexa |
|
|
|
Zinc Finger Protein 480 (ZNF480) Antibody |
abx030192-400ul |
Abbexa |
400 ul |
EUR 523 |
|
Zinc Finger Protein 480 (ZNF480) Antibody |
abx030192-80l |
Abbexa |
80 µl |
EUR 286 |
|
Polyclonal TAOK1 / TAO1 Antibody (aa431-480) |
AMM08087G |
Leading Biology |
0.05ml |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TAOK1 / TAO1 (aa431-480). This antibody is tested and proven to work in the following applications: |
Myosin Light Chain Kinase (480-501) |
H-3554.0500 |
Bachem |
0.5mg |
EUR 273 |
Description: Sum Formula: C120H209N41O28S2; CAS# [313642-00-1] |
Myosin Light Chain Kinase (480-501) |
H-3554.1000 |
Bachem |
1.0mg |
EUR 466 |
Description: Sum Formula: C120H209N41O28S2; CAS# [313642-00-1] |
SSEA-1 Antibody (Clone MC-480) |
3063-25 |
Biovision |
|
EUR 272 |
amfiSure PCR Premix, 8-Strip 0.2ml tube with Individual attached cap |
P0316-480 |
GenDepot |
5X96 rxns |
EUR 529 |
amfiEco PCR Premix |
P0702-480 |
GenDepot |
5x96 rxns |
EUR 444 |
amfiRivert 1-Step RT-PCR Premix |
R5004-480 |
GenDepot |
5x96 rxns |
EUR 928 |
Recombinant (E.Coli, GST tag) Hepatitis C Virus (HCV) NS5 Genotype-4 |
RP-480 |
Alpha Diagnostics |
100 ug |
EUR 286 |
WST-1 Cell Proliferation Colorimetric Assay Kit |
K2021-480 |
ApexBio |
480 assays |
EUR 321 |
TSLP (R127A, R130A) Recombinant Protein |
11-480 |
ProSci |
0.1 mg |
EUR 595.25 |
Description: Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine involved in the pathology of inflammatory skin diseases, and is widely expressed by epithelial cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence (4, 5). Human TSLP has been shown to developing nondeletional central tolerance, amplifying epithelium-induced class switching, inducing atopic diseases and maintaining intestinal noninflammatory environment. Among diverse cells responding to Human TSLP, CD11c+ dendritic cells are the most obviously characterized target cells. |
IL-4 Recombinant Protein |
90-480 |
ProSci |
10 ug |
EUR 364.25 |
Description: Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages. |
Reg1 alpha Recombinant Protein |
91-480 |
ProSci |
0.05 mg |
EUR 542.75 |
Description: Regenerating Islet-Derived Protein 1- alpha (REG1A) belongs to the Reg family of secreted proteins with a C-type lectic domain. REG1A is highly expressed levels in fetal and infant brains, much lower in adult brains. REG1A promotes the maintenance and growth of pancreatic islet cells and intestinal villi. In addition to, REG1A Might act as an inhibitor of spontaneous calcium carbonate precipitation and be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. |
IL-2 R beta Recombinant Protein |
92-480 |
ProSci |
0.05 mg |
EUR 684.5 |
Description: Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs. |
Transmembrane Protein 111 (TM111) Antibody |
abx032614-400ul |
Abbexa |
400 ul |
EUR 523 |
|
Transmembrane Protein 111 (TM111) Antibody |
abx032614-80l |
Abbexa |
80 µl |
EUR 286 |
|
Prepro VIP (111-122) (human) |
5-01793 |
CHI Scientific |
4 x 5mg |
Ask for price |
Prepro VIP (111-122) Peptide |
20-abx265194 |
Abbexa |
-
EUR 495.00
-
EUR 815.00
-
EUR 356.00
|
|
|
Recombinant ASFV Ken-111 Protein |
VAng-2105Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: African swine fever virus (isolate Pig/Kenya/KEN-50/1950) Probable DNA-directed RNA polymerase subunit 1 homolog (Ken-111), partial, recombinant protein from E. coli. (Uniprot ID: P0C989) |
Recombinant ASFV Pret-111 Protein |
VAng-2401Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996) Probable DNA-directed RNA polymerase subunit 1 homolog (Pret-111), partial, recombinant protein from E. coli. (Uniprot ID: P0C987) |
Recombinant ASFV War-111 Protein |
VAng-2507Lsx-inquire |
Creative Biolabs |
inquire |
Ask for price |
Description: African swine fever virus (isolate Warthog/Namibia/Wart80/1980) Probable mRNA-capping enzyme (War-111), partial, recombinant protein from E. coli. (Uniprot ID: P0C994) |
Recombinant Rat Akt1 Protein (aa 1-480) |
VAng-2932Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 5590 |
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196) |
Recombinant Rat Akt1 Protein (aa 1-480) |
VAng-2932Lsx-200g |
Creative Biolabs |
200 µg |
EUR 3363 |
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196) |
Recombinant Rat Akt1 Protein (aa 1-480) |
VAng-2932Lsx-50g |
Creative Biolabs |
50 µg |
EUR 2525 |
Description: Recombinant Rat Akt1 is expressed in E. coli. (Uniprot ID: P47196) |
Recombinant Mouse Akt1 Protein (aa 1-480) |
VAng-2933Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 5590 |
Description: Recombinant Mouse Akt1 is expressed in E. coli. (Uniprot ID: P31750) |
We detect signatures of positive selection across several genes related to the development and regulation of the forebrain, hormones, and the iguanian lizard dewlap, suggesting molecular changes underlying behavioral adaptations known to reinforce species boundaries were a key component in the diversification of anolelizards.